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Targeting CYP2J2 to Enhance the Anti-Glioma Efficacy of Cannabinoid Receptor 2 Stimulation by Inhibiting the Pro-Angiogenesis Function of M2 Microglia

Enhancing the therapeutic efficacy of anti-tumor drugs is essential for cancer management. Although cannabinoid receptor 2 (CB2R) stimulation exerts anti-tumor action in glioma cells by regulating cellular proliferation, differentiation, or apoptosis, selective CB2R agonist alone does not achieve a...

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Detalles Bibliográficos
Autores principales: Lei, Xuejiao, Chen, Xuezhu, Quan, Yulian, Tao, Yihao, Li, Junlong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7729163/
https://www.ncbi.nlm.nih.gov/pubmed/33330047
http://dx.doi.org/10.3389/fonc.2020.574277