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Human retinal pigment epithelial cells are protected against hypoxia by BNIP3

BACKGROUND: Hypoxia has been implicated in the process of retinal pigment epithelium (RPE) dysfunction. However, recent studies suggest that hypoxia contributes to survival rather than cell death through induction of Bcl-2/adenovirus E1B 19-kDa interacting protein 3 (BNIP3)-dependent autophagy. In c...

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Detalles Bibliográficos
Autores principales: Feng, Jingyang, Tan, Wei, Li, Tong, Yan, Quan, Zhu, Hong, Sun, Xiaodong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: AME Publishing Company 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7729317/
https://www.ncbi.nlm.nih.gov/pubmed/33313247
http://dx.doi.org/10.21037/atm-20-7145