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Establishment of multiplex allele-specific blocker PCR for enrichment and detection of 4 common EGFR mutations in non-small cell lung cancer

BACKGROUND: Lung cancer is one of the most severe cancers and the majority of patients miss the best timing for surgery when diagnosed, thus having to rely on radiotherapy, chemotherapy or target therapy. Epidermal growth factor receptor (EGFR) upregulation occurs in a large percentage of patients,...

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Detalles Bibliográficos
Autores principales: Chen, Hongyuan, Zhang, Jie, Chen, Hong-Yan, Su, Bo, Lu, Daru
Formato: Online Artículo Texto
Lenguaje:English
Publicado: AME Publishing Company 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7729377/
https://www.ncbi.nlm.nih.gov/pubmed/33313254
http://dx.doi.org/10.21037/atm-20-6754