MicroRNA-25-3p therapy for intervertebral disc degeneration by targeting the IL-1β/ZIP8/MTF1 signaling pathway with a novel thermo-responsive vector

BACKGROUND: MicroRNAs play important roles in intervertebral disc degeneration (IDD). The therapeutic effects of miRNA-25-3p on IDD and underlying mechanism are unclear. METHODS: Normal and degenerated nuclear pulposus (NP) tissue were collected. Primary NP cells were isolated and treated with diffe...

Descripción completa

Detalles Bibliográficos
Autores principales: Huang, Yong, Huang, Leizhen, Li, Li, Ge, Zhishen, Feng, Ganjun, Liu, Limin, Song, Yueming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: AME Publishing Company 2020
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7729380/
https://www.ncbi.nlm.nih.gov/pubmed/33313245
http://dx.doi.org/10.21037/atm-20-6595

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7729380/
https://www.ncbi.nlm.nih.gov/pubmed/33313245
http://dx.doi.org/10.21037/atm-20-6595

Ejemplares similares