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Genetic Deficiency and Pharmacological Stabilization of Mast Cells Ameliorate Pressure Overload-Induced Maladaptive Right Ventricular Remodeling in Mice

Although the response of the right ventricle (RV) to the increased afterload is an important determinant of the patient outcome, very little is known about the underlying mechanisms. Mast cells have been implicated in the pathogenesis of left ventricular maladaptive remodeling and failure. However,...

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Detalles Bibliográficos
Autores principales: Sydykov, Akylbek, Luitel, Himal, Mamazhakypov, Argen, Wygrecka, Malgorzata, Pradhan, Kabita, Pak, Oleg, Petrovic, Aleksandar, Kojonazarov, Baktybek, Weissmann, Norbert, Seeger, Werner, Grimminger, Friedrich, Ghofrani, Hossein Ardeschir, Kosanovic, Djuro, Schermuly, Ralph Theo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7729505/
https://www.ncbi.nlm.nih.gov/pubmed/33265921
http://dx.doi.org/10.3390/ijms21239099