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The Development of Maillard Reaction, and Advanced Glycation End Product (AGE)-Receptor for AGE (RAGE) Signaling Inhibitors as Novel Therapeutic Strategies for Patients with AGE-Related Diseases

Advanced glycation end products (AGEs) are generated by nonenzymatic modifications of macromolecules (proteins, lipids, and nucleic acids) by saccharides (glucose, fructose, and pentose) via Maillard reaction. The formed AGE molecules can be catabolized and cleared by glyoxalase I and II in renal pr...

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Detalles Bibliográficos
Autores principales: Shen, Chieh-Yu, Lu, Cheng-Hsun, Wu, Cheng-Han, Li, Ko-Jen, Kuo, Yu-Min, Hsieh, Song-Chou, Yu, Chia-Li
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7729569/
https://www.ncbi.nlm.nih.gov/pubmed/33261212
http://dx.doi.org/10.3390/molecules25235591