Phorbol 12-Myristate 13-Acetate Induced Toxicity Study and the Role of Tangeretin in Abrogating HIF-1α-NF-κB Crosstalk In Vitro and In Vivo

Phorbol 12-myristate 13-acetate (PMA) is a potent tumor promoter and highly inflammatory in nature. Here, we investigated the toxic effects of PMA on different model system. PMA (10 μg) caused chromosomal aberrations on the Allium cepa root tip and induced mitotic dysfunction. Similarly, PMA caused...

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Detalles Bibliográficos
Autores principales: Chang, Sukkum Ngullie, Dey, Debasish Kumar, Oh, Seong Taek, Kong, Won Ho, Cho, Kiu Hyung, Al-Olayan, Ebtesam M., Hwang, Buyng Su, Kang, Sun Chul, Park, Jae Gyu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7729754/
https://www.ncbi.nlm.nih.gov/pubmed/33291656
http://dx.doi.org/10.3390/ijms21239261

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7729754/
https://www.ncbi.nlm.nih.gov/pubmed/33291656
http://dx.doi.org/10.3390/ijms21239261

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