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The Role of β-Arrestins in Regulating Stem Cell Phenotypes in Normal and Tumorigenic Cells

β-Arrestins (ARRBs) are ubiquitously expressed scaffold proteins that mediate inactivation of G-protein-coupled receptor signaling, and in certain circumstances, G-protein independent pathways. Intriguingly, the two known ARRBs, β-arrestin1 (ARRB1) and β-Arrestin2 (ARRB2), seem to have opposing func...

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Detalles Bibliográficos
Autores principales: Kallifatidis, Georgios, Mamouni, Kenza, Lokeshwar, Bal L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7729818/
https://www.ncbi.nlm.nih.gov/pubmed/33297302
http://dx.doi.org/10.3390/ijms21239310