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Influence of Fluorination on Single-Molecule Unfolding and Rupture Pathways of a Mechanostable Protein Adhesion Complex

[Image: see text] We investigated the influence of fluorination on unfolding and unbinding reaction pathways of a mechanostable protein complex comprising the tandem dyad XModule-Dockerin bound to Cohesin. Using single-molecule atomic force spectroscopy, we mapped the energy landscapes governing the...

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Detalles Bibliográficos
Autores principales: Yang, Byeongseon, Liu, Haipei, Liu, Zhaowei, Doenen, Regina, Nash, Michael A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2020
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7729889/
https://www.ncbi.nlm.nih.gov/pubmed/33191756
http://dx.doi.org/10.1021/acs.nanolett.0c04178