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Modulation of Amyloidogenic Protein Self-Assembly Using Tethered Small Molecules
[Image: see text] Protein–protein interactions (PPIs) are involved in many of life’s essential biological functions yet are also an underlying cause of several human diseases, including amyloidosis. The modulation of PPIs presents opportunities to gain mechanistic insights into amyloid assembly, par...
Autores principales: | Cawood, Emma E., Guthertz, Nicolas, Ebo, Jessica S., Karamanos, Theodoros K., Radford, Sheena E., Wilson, Andrew J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Chemical
Society
2020
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7729939/ https://www.ncbi.nlm.nih.gov/pubmed/33253560 http://dx.doi.org/10.1021/jacs.0c10629 |
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