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Involvement of NMDA receptors containing the GluN2C subunit in the psychotomimetic and antidepressant-like effects of ketamine

Acute ketamine administration evokes rapid and sustained antidepressant effects in treatment-resistant patients. However, ketamine also produces transient perceptual disturbances similarly to those evoked by other non-competitive NMDA-R antagonists like phencyclidine (PCP). Although the brain networ...

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Detalles Bibliográficos
Autores principales: Tarrés-Gatius, Mireia, Miquel-Rio, Lluís, Campa, Leticia, Artigas, Francesc, Castañé, Anna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7729946/
https://www.ncbi.nlm.nih.gov/pubmed/33303736
http://dx.doi.org/10.1038/s41398-020-01110-y