A One-Pot Three-Component Synthesis and Investigation of the In Vitro Mechanistic Anticancer Activity of Highly Functionalized Spirooxindole-Pyrrolidine Heterocyclic Hybrids

With an aim to develop more effective and affordable anticancer agents possessing a unique mechanism of action, we designed and synthesized derivatives of spirooxindole-pyrrolidine heterocyclic hybrids in good yields through a one-pot three-component (3+2) cycloaddition strategy. The synthesized com...

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Detalles Bibliográficos
Autores principales: Kumar, Raju Suresh, M. Al-thamili, Dhaifallah, Almansour, Abdulrahman I., Arumugam, Natarajan, Mohammad, Faruq
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7730040/
https://www.ncbi.nlm.nih.gov/pubmed/33261115
http://dx.doi.org/10.3390/molecules25235581

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7730040/
https://www.ncbi.nlm.nih.gov/pubmed/33261115
http://dx.doi.org/10.3390/molecules25235581

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