Self-Assembly of pH-Labile Polymer Nanoparticles for Paclitaxel Prodrug Delivery: Formulation, Characterization, and Evaluation

The efficacy of paclitaxel (PTX) is limited due to its poor solubility, poor bioavailability, and acquired drug resistance mechanisms. Designing paclitaxel prodrugs can improve its anticancer activity and enable formulation of nanoparticles. Overall, the aim of this work is to improve the potency of...

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Detalles Bibliográficos
Autores principales: Levit, Shani L., Gade, Narendar Reddy, Roper, Thomas D., Yang, Hu, Tang, Christina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7730096/
https://www.ncbi.nlm.nih.gov/pubmed/33291475
http://dx.doi.org/10.3390/ijms21239292

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7730096/
https://www.ncbi.nlm.nih.gov/pubmed/33291475
http://dx.doi.org/10.3390/ijms21239292

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