The Therapeutic Potential of Neuronal K-Cl Co-Transporter KCC2 in Huntington’s Disease and Its Comorbidities

Intracellular chloride levels in the brain are regulated primarily through the opposing effects of two cation-chloride co-transporters (CCCs), namely K(+)-Cl(−) co-transporter-2 (KCC2) and Na(+)-K(+)-Cl(−) co-transporter-1 (NKCC1). These CCCs are differentially expressed throughout the course of dev...

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Detalles Bibliográficos
Autores principales: Andrews, Katie, Josiah, Sunday Solomon, Zhang, Jinwei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7730145/
https://www.ncbi.nlm.nih.gov/pubmed/33266310
http://dx.doi.org/10.3390/ijms21239142

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7730145/
https://www.ncbi.nlm.nih.gov/pubmed/33266310
http://dx.doi.org/10.3390/ijms21239142

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