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The Mechanisms Underlying Autonomous Adrenocorticotropic Hormone Secretion in Cushing’s Disease

Cushing’s disease caused due to adrenocorticotropic hormone (ACTH)-secreting pituitary adenomas (ACTHomas) leads to hypercortisolemia, resulting in increased morbidity and mortality. Autonomous ACTH secretion is attributed to the impaired glucocorticoid negative feedback (glucocorticoid resistance)...

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Detalles Bibliográficos
Autores principales: Fukuoka, Hidenori, Shichi, Hiroki, Yamamoto, Masaaki, Takahashi, Yutaka
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7730156/
https://www.ncbi.nlm.nih.gov/pubmed/33266265
http://dx.doi.org/10.3390/ijms21239132