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Peptide-Affinity Precipitation of Extracellular Vesicles and Cell-Free DNA Improves Sequencing Performance for the Detection of Pathogenic Mutations in Lung Cancer Patient Plasma

Liquid biopsy is a minimally-invasive diagnostic method that may improve access to molecular profiling for non-small cell lung cancer (NSCLC) patients. Although cell-free DNA (cf-DNA) isolation from plasma is the standard liquid biopsy method for detecting DNA mutations in cancer patients, the sensi...

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Detalles Bibliográficos
Autores principales: Taylor, Catherine, Chacko, Simi, Davey, Michelle, Lacroix, Jacynthe, MacPherson, Alexander, Finn, Nicholas, Wajnberg, Gabriel, Ghosh, Anirban, Crapoulet, Nicolas, Lewis, Stephen M., Ouellette, Rodney J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7730179/
https://www.ncbi.nlm.nih.gov/pubmed/33260345
http://dx.doi.org/10.3390/ijms21239083