Different Sensitivity of Control and MICU1- and MICU2-Ablated Trypanosoma cruzi Mitochondrial Calcium Uniporter Complex to Ruthenium-Based Inhibitors

The mitochondrial Ca(2+) uptake in trypanosomatids shares biochemical characteristics with that of animals. However, the composition of the mitochondrial Ca(2+) uniporter complex (MCUC) in these parasites is quite peculiar, suggesting lineage-specific adaptations. In this work, we compared the inhib...

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Detalles Bibliográficos
Autores principales: Bertolini, Mayara S., Docampo, Roberto
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7730205/
https://www.ncbi.nlm.nih.gov/pubmed/33297372
http://dx.doi.org/10.3390/ijms21239316

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7730205/
https://www.ncbi.nlm.nih.gov/pubmed/33297372
http://dx.doi.org/10.3390/ijms21239316

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