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Different Sensitivity of Control and MICU1- and MICU2-Ablated Trypanosoma cruzi Mitochondrial Calcium Uniporter Complex to Ruthenium-Based Inhibitors
The mitochondrial Ca(2+) uptake in trypanosomatids shares biochemical characteristics with that of animals. However, the composition of the mitochondrial Ca(2+) uniporter complex (MCUC) in these parasites is quite peculiar, suggesting lineage-specific adaptations. In this work, we compared the inhib...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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MDPI
2020
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7730205/ https://www.ncbi.nlm.nih.gov/pubmed/33297372 http://dx.doi.org/10.3390/ijms21239316 |