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2-Deoxy-d-glucose Promotes Buforin IIb-Induced Cytotoxicity in Prostate Cancer DU145 Cells and Xenograft Tumors

Inhibition of the glycolytic pathway is a critical strategy in anticancer therapy because of the role of aerobic glycolysis in cancer cells. The glycolytic inhibitor 2-Deoxy-d-glucose (2-DG) has shown potential in combination with other anticancer agents. Buforin IIb is an effective antimicrobial pe...

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Detalles Bibliográficos
Autores principales: Wanyan, Yangke, Xu, Xixi, Liu, Kehang, Zhang, Huidan, Zhen, Junai, Zhang, Rong, Wen, Jumei, Liu, Ping, Chen, Yuqing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7730206/
https://www.ncbi.nlm.nih.gov/pubmed/33297583
http://dx.doi.org/10.3390/molecules25235778