Temporin-Like Peptides Show Antimicrobial and Anti-Biofilm Activities against Streptococcus mutans with Reduced Hemolysis

In our previous study, temporin-GHaR (GHaR) showed potent antimicrobial activity with strong hemolytic toxicity. To overcome its weakness, we designed GHaR6R, GHaR7R, GHaR8R, GHaR9R, and GHaR9W by changing the number of positive charges and the hydrophobic surface of GHaR. With the exception of GHaR...

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Detalles Bibliográficos
Autores principales: Wei, Hanqi, Xie, Zhipeng, Tan, Xiuchuan, Guo, Ran, Song, Yanting, Xie, Xi, Wang, Rong, Li, Lushuang, Wang, Manchuriga, Zhang, Yingxia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7730238/
https://www.ncbi.nlm.nih.gov/pubmed/33291521
http://dx.doi.org/10.3390/molecules25235724

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7730238/
https://www.ncbi.nlm.nih.gov/pubmed/33291521
http://dx.doi.org/10.3390/molecules25235724

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