The STING-IFN-β-Dependent Axis Is Markedly Low in Patients with Relapsing-Remitting Multiple Sclerosis

Cyclic GMP-AMP-synthase is a sensor of endogenous nucleic acids, which subsequently elicits a stimulator of interferon genes (STING)-dependent type I interferon (IFN) response defending us against viruses and other intracellular pathogens. This pathway can drive pathological inflammation, as documen...

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Detalles Bibliográficos
Autores principales: Masanneck, Lars, Eichler, Susann, Vogelsang, Anna, Korsen, Melanie, Wiendl, Heinz, Budde, Thomas, Meuth, Sven G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7730283/
https://www.ncbi.nlm.nih.gov/pubmed/33291536
http://dx.doi.org/10.3390/ijms21239249

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7730283/
https://www.ncbi.nlm.nih.gov/pubmed/33291536
http://dx.doi.org/10.3390/ijms21239249

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