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Insight into Cisplatin-Resistance Signaling of W1 Ovarian Cancer Cells Emerges mTOR and HSP27 as Targets for Sensitization Strategies

The microenvironment possesses a strong impact on the tumor chemoresistance when cells bind to components of the extracellular matrix. Here we elucidate the signaling pathways of cisplatin resistance in W1 ovarian cancer cells binding to collagen type 1 (COL1) and signaling interference with constit...

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Detalles Bibliográficos
Autores principales: Wantoch von Rekowski, Kathleen, König, Philipp, Henze, Svenja, Schlesinger, Martin, Zawierucha, Piotr, Januchowski, Radosław, Bendas, Gerd
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7730285/
https://www.ncbi.nlm.nih.gov/pubmed/33287446
http://dx.doi.org/10.3390/ijms21239240