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Insight into Cisplatin-Resistance Signaling of W1 Ovarian Cancer Cells Emerges mTOR and HSP27 as Targets for Sensitization Strategies
The microenvironment possesses a strong impact on the tumor chemoresistance when cells bind to components of the extracellular matrix. Here we elucidate the signaling pathways of cisplatin resistance in W1 ovarian cancer cells binding to collagen type 1 (COL1) and signaling interference with constit...
Autores principales: | Wantoch von Rekowski, Kathleen, König, Philipp, Henze, Svenja, Schlesinger, Martin, Zawierucha, Piotr, Januchowski, Radosław, Bendas, Gerd |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7730285/ https://www.ncbi.nlm.nih.gov/pubmed/33287446 http://dx.doi.org/10.3390/ijms21239240 |
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