Enhancement in Phospholipase D Activity as a New Proposed Molecular Mechanism of Haloperidol-Induced Neurotoxicity

Membrane phospholipase D (PLD) is associated with numerous neuronal functions, such as axonal growth, synaptogenesis, formation of secretory vesicles, neurodegeneration, and apoptosis. PLD acts mainly on phosphatidylcholine, from which phosphatidic acid (PA) and choline are formed. In turn, PA is a...

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Detalles Bibliográficos
Autores principales: Krzystanek, Marek, Krzystanek, Ewa, Skałacka, Katarzyna, Pałasz, Artur
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7730321/
https://www.ncbi.nlm.nih.gov/pubmed/33291692
http://dx.doi.org/10.3390/ijms21239265

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7730321/
https://www.ncbi.nlm.nih.gov/pubmed/33291692
http://dx.doi.org/10.3390/ijms21239265

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