Do TUNEL and Other Apoptosis Assays Detect Cell Death in Preclinical Studies?

The terminal deoxynucleotidyl transferase-mediated dUTP nick end labeling (TUNEL) assay detects DNA breakage by labeling the free 3ʹ-hydroxyl termini. Given that genomic DNA breaks arise during early and late stages of apoptosis, TUNEL staining continues to be widely used as a measure of apoptotic c...

Descripción completa

Detalles Bibliográficos
Autores principales: Mirzayans, Razmik, Murray, David
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7730366/
https://www.ncbi.nlm.nih.gov/pubmed/33260475
http://dx.doi.org/10.3390/ijms21239090

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7730366/
https://www.ncbi.nlm.nih.gov/pubmed/33260475
http://dx.doi.org/10.3390/ijms21239090

Ejemplares similares