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Do TUNEL and Other Apoptosis Assays Detect Cell Death in Preclinical Studies?
The terminal deoxynucleotidyl transferase-mediated dUTP nick end labeling (TUNEL) assay detects DNA breakage by labeling the free 3ʹ-hydroxyl termini. Given that genomic DNA breaks arise during early and late stages of apoptosis, TUNEL staining continues to be widely used as a measure of apoptotic c...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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MDPI
2020
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7730366/ https://www.ncbi.nlm.nih.gov/pubmed/33260475 http://dx.doi.org/10.3390/ijms21239090 |