Rational Computational Design of Fourth-Generation EGFR Inhibitors to Combat Drug-Resistant Non-Small Cell Lung Cancer

Although the inhibitors of singly mutated epidermal growth factor receptor (EGFR) kinase are effective for the treatment of non-small cell lung cancer (NSCLC), their clinical efficacy has been limited due to the emergence of various double and triple EGFR mutants with drug resistance. It has thus be...

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Detalles Bibliográficos
Autores principales: Park, Hwangseo, Jung, Hoi-Yun, Kim, Kewon, Kim, Myojeong, Hong, Sungwoo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7730458/
https://www.ncbi.nlm.nih.gov/pubmed/33297461
http://dx.doi.org/10.3390/ijms21239323

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7730458/
https://www.ncbi.nlm.nih.gov/pubmed/33297461
http://dx.doi.org/10.3390/ijms21239323

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