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Gremlin-1 Promotes Metastasis of Breast Cancer Cells by Activating STAT3-MMP13 Signaling Pathway

Gremlin-1 (GREM1), one of the bone morphogenetic protein (BMP) antagonists, can directly bind to BMPs. GREM1 is involved in organogenesis, tissue differentiation, and organ fibrosis. Recently, numerous studies have reported the oncogenic role of GREM1 in cancer. However, the role of GREM1 in metasta...

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Detalles Bibliográficos
Autores principales: Sung, Nam Ji, Kim, Na Hui, Surh, Young-Joon, Park, Sin-Aye
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7730512/
https://www.ncbi.nlm.nih.gov/pubmed/33287358
http://dx.doi.org/10.3390/ijms21239227