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A Celecoxib Derivative Eradicates Antibiotic-Resistant Staphylococcus aureus and Biofilms by Targeting YidC2 Translocase

The treatment of Staphylococcus aureus infections is impeded by the prevalence of MRSA and the formation of persisters and biofilms. Previously, we identified two celecoxib derivatives, Cpd36 and Cpd46, to eradicate MRSA and other staphylococci. Through whole-genome resequencing, we obtained several...

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Detalles Bibliográficos
Autores principales: Tzeng, Shiou-Ru, Huang, Yi-Wei, Zhang, Yao-Qing, Yang, Ching-Yi, Chien, Han-Sheng, Chen, Yi-Ru, Yu, Sung-Liang, Chen, Ching S., Chiu, Hao-Chieh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7730571/
https://www.ncbi.nlm.nih.gov/pubmed/33297331
http://dx.doi.org/10.3390/ijms21239312