Cargando…
A Celecoxib Derivative Eradicates Antibiotic-Resistant Staphylococcus aureus and Biofilms by Targeting YidC2 Translocase
The treatment of Staphylococcus aureus infections is impeded by the prevalence of MRSA and the formation of persisters and biofilms. Previously, we identified two celecoxib derivatives, Cpd36 and Cpd46, to eradicate MRSA and other staphylococci. Through whole-genome resequencing, we obtained several...
Autores principales: | Tzeng, Shiou-Ru, Huang, Yi-Wei, Zhang, Yao-Qing, Yang, Ching-Yi, Chien, Han-Sheng, Chen, Yi-Ru, Yu, Sung-Liang, Chen, Ching S., Chiu, Hao-Chieh |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2020
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7730571/ https://www.ncbi.nlm.nih.gov/pubmed/33297331 http://dx.doi.org/10.3390/ijms21239312 |
Ejemplares similares
-
The preprotein translocase YidC controls respiratory metabolism in Mycobacterium tuberculosis
por: Thakur, Preeti, et al.
Publicado: (2016) -
Fates of Sec, Tat, and YidC Translocases in Mitochondria and Other Eukaryotic Compartments
por: Petrů, Markéta, et al.
Publicado: (2021) -
Molecular communication of the membrane insertase YidC with translocase SecYEG affects client proteins
por: Steudle, Anja, et al.
Publicado: (2021) -
Role of YidC in folding of polytopic membrane proteins
por: Nagamori, Shushi, et al.
Publicado: (2004) -
Regulation and overexpression studies of YidC in Mycobacterium tuberculosis
por: Thakur, Preeti, et al.
Publicado: (2018)