Application of the RBBP9 Serine Hydrolase Inhibitor, ML114, Decouples Human Pluripotent Stem Cell Proliferation and Differentiation

Retinoblastoma binding protein 9 (RBBP9) is required for maintaining the expression of both pluripotency and cell cycle genes in human pluripotent stem cells (hPSCs). An siRNA-based study from our group showed it does so by influencing cell cycle progression through the RB/E2F pathway. In non-plurip...

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Detalles Bibliográficos
Autores principales: Lim, Seakcheng, Shparberg, Rachel A., Coorssen, Jens R., O’Connor, Michael D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7730578/
https://www.ncbi.nlm.nih.gov/pubmed/33256189
http://dx.doi.org/10.3390/ijms21238983

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7730578/
https://www.ncbi.nlm.nih.gov/pubmed/33256189
http://dx.doi.org/10.3390/ijms21238983

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