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Myeloperoxidase-Derived 2-Chlorohexadecanal Is Generated in Mouse Heart during Endotoxemia and Induces Modification of Distinct Cardiomyocyte Protein Subsets In Vitro

Sepsis is a major cause of mortality in critically ill patients and associated with cardiac dysfunction, a complication linked to immunological and metabolic aberrations. Cardiac neutrophil infiltration and subsequent release of myeloperoxidase (MPO) leads to the formation of the oxidant hypochlorou...

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Detalles Bibliográficos
Autores principales: Prasch, Jürgen, Bernhart, Eva, Reicher, Helga, Kollroser, Manfred, Rechberger, Gerald N., Koyani, Chintan N., Trummer, Christopher, Rech, Lavinia, Rainer, Peter P., Hammer, Astrid, Malle, Ernst, Sattler, Wolfgang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7730634/
https://www.ncbi.nlm.nih.gov/pubmed/33287422
http://dx.doi.org/10.3390/ijms21239235