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Liposomes Composed by Membrane Lipid Extracts from Macrophage Cell Line as a Delivery of the Trypanocidal N,N’-Squaramide 17 towards Trypanosoma cruzi

Chagas is a neglected tropical disease caused by Trypanosoma cruzi, and affects about 25 million people worldwide. N, N’-Squaramide 17 (S) is a trypanocidal compound with relevant in vivo effectiveness. Here, we produced, characterized, and evaluated cytotoxic and trypanocidal effects of macrophage-...

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Detalles Bibliográficos
Autores principales: Quijia, Christian Rafael, Bonatto, Cínthia Caetano, Silva, Luciano Paulino, Andrade, Milene Aparecida, Azevedo, Clenia Santos, Lasse Silva, Camila, Vega, Manel, de Santana, Jaime Martins, Bastos, Izabela Marques Dourado, Carneiro, Marcella Lemos Brettas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7730638/
https://www.ncbi.nlm.nih.gov/pubmed/33276688
http://dx.doi.org/10.3390/ma13235505