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Quinolones: Mechanism, Lethality and Their Contributions to Antibiotic Resistance

Fluoroquinolones (FQs) are arguably among the most successful antibiotics of recent times. They have enjoyed over 30 years of clinical usage and become essential tools in the armoury of clinical treatments. FQs target the bacterial enzymes DNA gyrase and DNA topoisomerase IV, where they stabilise a...

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Detalles Bibliográficos
Autores principales: Bush, Natassja G., Diez-Santos, Isabel, Abbott, Lauren R., Maxwell, Anthony
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7730664/
https://www.ncbi.nlm.nih.gov/pubmed/33271787
http://dx.doi.org/10.3390/molecules25235662