Mutational Analysis of the Nsa2 N-Terminus Reveals Its Essential Role in Ribosomal 60S Subunit Assembly

The ribosome assembly factor Nsa2 is part of the Rea1-Rsa4-Nsa2 interconnected relay on nuclear pre-60S particles that is essential for 60S ribosome biogenesis. Cryo-EM structures depict Nsa2 docked via its C-terminal β-barrel domain to nuclear pre-60S particles, whereas the extended N-terminus, con...

Descripción completa

Detalles Bibliográficos
Autores principales: Paternoga, Helge, Früh, Alexander, Kunze, Ruth, Bradatsch, Bettina, Baßler, Jochen, Hurt, Ed
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7730687/
https://www.ncbi.nlm.nih.gov/pubmed/33266193
http://dx.doi.org/10.3390/ijms21239108

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7730687/
https://www.ncbi.nlm.nih.gov/pubmed/33266193
http://dx.doi.org/10.3390/ijms21239108

Ejemplares similares