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Expressing a cytosolic pyruvate dehydrogenase complex to increase free fatty acid production in Saccharomyces cerevisiae

BACKGROUND: Saccharomyces cerevisiae is being exploited as a cell factory to produce fatty acids and their derivatives as biofuels. Previous studies found that both precursor supply and fatty acid metabolism deregulation are essential for enhanced fatty acid synthesis. A bacterial pyruvate dehydroge...

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Detalles Bibliográficos
Autores principales: Zhang, Yiming, Su, Mo, Qin, Ning, Nielsen, Jens, Liu, Zihe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7730738/
https://www.ncbi.nlm.nih.gov/pubmed/33302960
http://dx.doi.org/10.1186/s12934-020-01493-z