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Designing next generation recombinant protein expression platforms by modulating the cellular stress response in Escherichia coli
BACKGROUND: A cellular stress response (CSR) is triggered upon recombinant protein synthesis which acts as a global feedback regulator of protein expression. To remove this key regulatory bottleneck, we had previously proposed that genes that are up-regulated post induction could be part of the sign...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7730785/ https://www.ncbi.nlm.nih.gov/pubmed/33308214 http://dx.doi.org/10.1186/s12934-020-01488-w |