Mitochondrial dysfunction and consequences in calpain-3-deficient muscle

BACKGROUND: Nonsense or loss-of-function mutations in the non-lysosomal cysteine protease calpain-3 result in limb-girdle muscular dystrophy type 2A (LGMD2A). While calpain-3 is implicated in muscle cell differentiation, sarcomere formation, and muscle cytoskeletal remodeling, the physiological basi...

Descripción completa

Detalles Bibliográficos
Autores principales: Jahnke, Vanessa E., Peterson, Jennifer M., Van Der Meulen, Jack H., Boehler, Jessica, Uaesoontrachoon, Kitipong, Johnston, Helen K., Defour, Aurelia, Phadke, Aditi, Yu, Qing, Jaiswal, Jyoti K., Nagaraju, Kanneboyina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7730798/
https://www.ncbi.nlm.nih.gov/pubmed/33308300
http://dx.doi.org/10.1186/s13395-020-00254-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7730798/
https://www.ncbi.nlm.nih.gov/pubmed/33308300
http://dx.doi.org/10.1186/s13395-020-00254-1

Ejemplares similares