Cargando…

Global hypermethylation of intestinal epithelial cells is a hallmark feature of neonatal surgical necrotizing enterocolitis

BACKGROUND: Necrotizing enterocolitis (NEC) remains one of the overall leading causes of death in premature infants, and the pathogenesis is unpredictable and not well characterized. The aim of our study was to determine the molecular phenotype of NEC via transcriptomic and epithelial cell-specific...

Descripción completa

Detalles Bibliográficos
Autores principales: Good, Misty, Chu, Tianjiao, Shaw, Patricia, McClain, Lora, Chamberlain, Austin, Castro, Carlos, Rimer, Jamie M., Mihi, Belgacem, Gong, Qingqing, Nolan, Lila S., Cooksey, Krista, Linneman, Laura, Agrawal, Pranjal, Finegold, David N., Peters, David
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7730811/
https://www.ncbi.nlm.nih.gov/pubmed/33308304
http://dx.doi.org/10.1186/s13148-020-00983-6