Deciphering the Role of Filamin B Calponin-Homology Domain in Causing the Larsen Syndrome, Boomerang Dysplasia, and Atelosteogenesis Type I Spectrum Disorders via a Computational Approach

Filamins (FLN) are a family of actin-binding proteins involved in regulating the cytoskeleton and signaling phenomenon by developing a network with F-actin and FLN-binding partners. The FLN family comprises three conserved isoforms in mammals: FLNA, FLNB, and FLNC. FLNB is a multidomain monomer prot...

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Detalles Bibliográficos
Autores principales: S., Udhaya Kumar, Sankar, Srivarshini, Younes, Salma, D., Thirumal Kumar, Ahmad, Muneera Naseer, Okashah, Sarah Samer, Kamaraj, Balu, Al-Subaie, Abeer Mohammed, C., George Priya Doss, Zayed, Hatem
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7730838/
https://www.ncbi.nlm.nih.gov/pubmed/33255942
http://dx.doi.org/10.3390/molecules25235543

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7730838/
https://www.ncbi.nlm.nih.gov/pubmed/33255942
http://dx.doi.org/10.3390/molecules25235543

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