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Deciphering the Role of Filamin B Calponin-Homology Domain in Causing the Larsen Syndrome, Boomerang Dysplasia, and Atelosteogenesis Type I Spectrum Disorders via a Computational Approach
Filamins (FLN) are a family of actin-binding proteins involved in regulating the cytoskeleton and signaling phenomenon by developing a network with F-actin and FLN-binding partners. The FLN family comprises three conserved isoforms in mammals: FLNA, FLNB, and FLNC. FLNB is a multidomain monomer prot...
Autores principales: | S., Udhaya Kumar, Sankar, Srivarshini, Younes, Salma, D., Thirumal Kumar, Ahmad, Muneera Naseer, Okashah, Sarah Samer, Kamaraj, Balu, Al-Subaie, Abeer Mohammed, C., George Priya Doss, Zayed, Hatem |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7730838/ https://www.ncbi.nlm.nih.gov/pubmed/33255942 http://dx.doi.org/10.3390/molecules25235543 |
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