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Effectiveness in Block by Dexmedetomidine of Hyperpolarization-Activated Cation Current, Independent of Its Agonistic Effect on α(2)-Adrenergic Receptors

Dexmedetomidine (DEX), a highly selective agonist of α(2)-adrenergic receptors, has been tailored for sedation without risk of respiratory depression. Our hypothesis is that DEX produces any direct perturbations on ionic currents (e.g., hyperpolarization-activated cation current, I(h)). In this stud...

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Detalles Bibliográficos
Autores principales:	Lu, Te-Ling, Lu, Te-Jung, Wu, Sheng-Nan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7730867/ https://www.ncbi.nlm.nih.gov/pubmed/33266068 http://dx.doi.org/10.3390/ijms21239110

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