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Current Synthetic Routes to Peptidyl Mono-Fluoromethyl Ketones (FMKs) and Their Applications

Peptidyl mono-fluoromethyl ketones (FMKs) are a class of biologically active molecules that show potential as both protease inhibitors for the treatment of a range of diseases and as chemical probes for the interrogation of cellular processes. This review describes the current solid- and solution-ph...

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Detalles Bibliográficos
Autores principales: Lloyd, Carissa M., Colgin, Neil, Cobb, Steven L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7730879/
https://www.ncbi.nlm.nih.gov/pubmed/33260551
http://dx.doi.org/10.3390/molecules25235601