Cargando…

Modulation of Brain Hyperexcitability: Potential New Therapeutic Approaches in Alzheimer’s Disease

People with Alzheimer’s disease (AD) have significantly higher rates of subclinical and overt epileptiform activity. In animal models, oligomeric Aβ amyloid is able to induce neuronal hyperexcitability even in the early phases of the disease. Such aberrant activity subsequently leads to downstream a...

Descripción completa

Detalles Bibliográficos
Autores principales: Toniolo, Sofia, Sen, Arjune, Husain, Masud
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7730926/
https://www.ncbi.nlm.nih.gov/pubmed/33297460
http://dx.doi.org/10.3390/ijms21239318