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Modulation of Brain Hyperexcitability: Potential New Therapeutic Approaches in Alzheimer’s Disease
People with Alzheimer’s disease (AD) have significantly higher rates of subclinical and overt epileptiform activity. In animal models, oligomeric Aβ amyloid is able to induce neuronal hyperexcitability even in the early phases of the disease. Such aberrant activity subsequently leads to downstream a...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7730926/ https://www.ncbi.nlm.nih.gov/pubmed/33297460 http://dx.doi.org/10.3390/ijms21239318 |