AGE-RAGE Axis Stimulates Oxidized LDL Uptake into Macrophages through Cyclin-Dependent Kinase 5-CD36 Pathway via Oxidative Stress Generation

Advanced glycation end products (AGEs) are localized in macrophage-derived foam cells within atherosclerotic lesions, which could be associated with the increased risk of atherosclerotic cardiovascular disease under diabetic conditions. Although foam cell formation of macrophages has been shown to b...

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Detalles Bibliográficos
Autores principales: Yashima, Hironori, Terasaki, Michishige, Sotokawauchi, Ami, Matsui, Takanori, Mori, Yusaku, Saito, Tomomi, Osaka, Naoya, Kushima, Hideki, Hiromura, Munenori, Ohara, Makoto, Fukui, Tomoyasu, Yamagishi, Sho-ichi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7730944/
https://www.ncbi.nlm.nih.gov/pubmed/33291667
http://dx.doi.org/10.3390/ijms21239263

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7730944/
https://www.ncbi.nlm.nih.gov/pubmed/33291667
http://dx.doi.org/10.3390/ijms21239263

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