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Triangular Relationship between p53, Autophagy, and Chemotherapy Resistance

Chemotherapy and radiation often induce a number of cellular responses, such as apoptosis, autophagy, and senescence. One of the major regulators of these processes is p53, an essential tumor suppressor that is often mutated or lost in many cancer types and implicated in early tumorigenesis. Gain of...

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Detalles Bibliográficos
Autores principales: Xu, Jingwen, Patel, Nipa H., Gewirtz, David A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7730978/
https://www.ncbi.nlm.nih.gov/pubmed/33256191
http://dx.doi.org/10.3390/ijms21238991