Cargando…
Triangular Relationship between p53, Autophagy, and Chemotherapy Resistance
Chemotherapy and radiation often induce a number of cellular responses, such as apoptosis, autophagy, and senescence. One of the major regulators of these processes is p53, an essential tumor suppressor that is often mutated or lost in many cancer types and implicated in early tumorigenesis. Gain of...
Autores principales: | Xu, Jingwen, Patel, Nipa H., Gewirtz, David A. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2020
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7730978/ https://www.ncbi.nlm.nih.gov/pubmed/33256191 http://dx.doi.org/10.3390/ijms21238991 |
Ejemplares similares
-
Is Autophagy Always a Barrier to Cisplatin Therapy?
por: Xu, Jingwen, et al.
Publicado: (2022) -
Studies of Non-Protective Autophagy Provide Evidence that Recovery from Therapy-Induced Senescence is Independent of Early Autophagy
por: Saleh, Tareq, et al.
Publicado: (2020) -
The Cytoprotective, Cytotoxic and Nonprotective Functional Forms of Autophagy Induced by Microtubule Poisons in Tumor Cells—Implications for Autophagy Modulation as a Therapeutic Strategy
por: Xu, Jingwen, et al.
Publicado: (2022) -
p53-Induced Autophagy Regulates Chemotherapy and Radiotherapy Resistance in Multidrug Resistance Cancer Cells
por: Ma, Shumei, et al.
Publicado: (2021) -
The role of p53 in cancer drug resistance and targeted chemotherapy
por: Hientz, Karin, et al.
Publicado: (2016)