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Activation and Delivery of Tetrazine-Responsive Bioorthogonal Prodrugs
Prodrugs, which remain inert until they are activated under appropriate conditions at the target site, have emerged as an attractive alternative to drugs that lack selectivity and show off-target effects. Prodrugs have traditionally been activated by enzymes, pH or other trigger factors associated w...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7731009/ https://www.ncbi.nlm.nih.gov/pubmed/33266075 http://dx.doi.org/10.3390/molecules25235640 |