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Activation and Delivery of Tetrazine-Responsive Bioorthogonal Prodrugs

Prodrugs, which remain inert until they are activated under appropriate conditions at the target site, have emerged as an attractive alternative to drugs that lack selectivity and show off-target effects. Prodrugs have traditionally been activated by enzymes, pH or other trigger factors associated w...

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Detalles Bibliográficos
Autores principales: Wang, Yayue, Zhang, Chang, Wu, Haoxing, Feng, Ping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7731009/
https://www.ncbi.nlm.nih.gov/pubmed/33266075
http://dx.doi.org/10.3390/molecules25235640

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