Interrelated Mechanism by Which the Methide Quinone Celastrol, Obtained from the Roots of Tripterygium wilfordii, Inhibits Main Protease 3CL(pro) of COVID-19 and Acts as Superoxide Radical Scavenger

We describe the potential anti coronavirus disease 2019 (COVID-19) action of the methide quinone inhibitor, celastrol. The related methide quinone dexamethasone is, so far, among COVID-19 medications perhaps the most effective drug for patients with severe symptoms. We observe a parallel redox biolo...

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Detalles Bibliográficos
Autores principales: Caruso, Francesco, Singh, Manrose, Belli, Stuart, Berinato, Molly, Rossi, Miriam
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7731079/
https://www.ncbi.nlm.nih.gov/pubmed/33291769
http://dx.doi.org/10.3390/ijms21239266

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7731079/
https://www.ncbi.nlm.nih.gov/pubmed/33291769
http://dx.doi.org/10.3390/ijms21239266

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